Archive: Biotechnology
Biotechnology 2007 Research Highlights
Prenatal diagnosis: Detection without invasion
Dangsheng Li
Published online: 19 December 2007 | doi:10.1038/nchina.2007.274
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et al. Plasma placental RNA allelic ratio permits non-invasive prenatal chromosomal aneuploidy detection. Nature Med. 13, 218–223 (2007).
Top of pageBiological nanotubes: Putting viruses into shape
Anne Pichon
Published online: 12 December 2007 | doi:10.1038/nchina.2007.264
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et al. DNA-templated CMV viral capsid proteins assemble into nanotubes. Chem. Commun. doi: 10.1039/b715299j (2007).
Top of pageUltraviolet response: A sunscreen for plants
Wei Zeng
Published online: 05 December 2007 | doi:10.1038/nchina.2007.257
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et al. SAD2, an importin
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-like protein, is required for UV-B response in Arabidopsis by mediating MYB4 nuclear trafficking. Plant Cell doi: 10.1105/tpc.106.048900 (2007).Cryopreservation: Electrically frozen this content is Open !
Tim Reid
Published online: 05 December 2007 | doi:10.1038/nchina.2007.259
Original article citation:
Effects of dipole polarization of water molecules on ice formation under an electrostatic field. Cryobiol. doi: 10.1016/j.cryobiol.2007.10.173 (2007).
Top of pageFungal insecticides: Now come with an extra sting
Felix Cheung
Published online: 28 November 2007 | doi:10.1038/nchina.2007.251
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A scorpion neurotoxin increases the potency of a fungal insecticide. Nature Biotechnol. doi: 10.1038/nbt1357 (2007).
Top of pageBipedal nanomotors: Asymmetry locked in
Wei Zeng
Published online: 28 November 2007 | doi:10.1038/nchina.2007.252
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Synergic mechanism and fabrication target for bipedal nanomotors. PNAS 104, 17921–17926 (2007).
Top of pagePest control: Plant defence
Felix Cheung
Published online: 21 November 2007 | doi:10.1038/nchina.2007.243
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et al. Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypol. Nature Biotechnol. doi: 10.1038/nbt1352 (2007).
Top of pageAntifungal proteins: The nutty killer
Felix Cheung
Published online: 14 November 2007 | doi:10.1038/nchina.2007.239
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Hypotin, a novel antipathogenic and antiproliferative protein from peanuts with a sequence similar to those of chitinase precursors. J. Agric. Food Chem. doi: 10.1021/jf071540j (2007).
Top of pageBlood lipid levels: The power of Chinese yams this content is Open !
Tim Reid
Published online: 14 November 2007 | doi:10.1038/nchina.2007.240
Original article citation:
Characterization and preliminary lipid-lowering evaluation of starch from Chinese yam. Food Chem. doi: 10.1016/j.foodchem.2007.10.059 (2007).
Top of pageNanochannels: Driven by charges
Wei Zeng
Published online: 14 November 2007 | doi:10.1038/nchina.2007.242
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et al. A charge-driven molecular water pump. Nature Nanotech. doi: 10.1038/nnano.2007.320 (2007).
Top of pageLipid degradation: Freezing and thawing this content is Open !
Wei Zeng
Published online: 07 November 2007 | doi:10.1038/nchina.2007.235
Original article citation:
et al. Differential degradation of extraplastidic and plastidic lipids during freezing and post-freezing recovery in Arabidopsis thaliana. J. Biol. Chem. doi: 10.1074/jbc.M706692200 (2007).
Top of pageHistone methylation: Take it away
Wei Zeng
Published online: 31 October 2007 | doi:10.1038/nchina.2007.230
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et al. JMJD3 is a histone H3K27 demethylase. Cell Res. 17, 850–857 (2007).
Top of pageProtein structure: Let's swap
Wei Zeng
Published online: 17 October 2007 | doi:10.1038/nchina.2007.218
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et al. Domain-swapped dimerization of the second PDZ domain of ZO2 may provide a structural basis for the polymerization of claudins. J. Biol. Chem. doi: 10.1074/jbc.M703826200 (2007).
Top of pageCarbon nanotubes: Becoming a brighter fighter
Felix Cheung
Published online: 12 September 2007 | doi:10.1038/nchina.2007.187
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et al. Intracellular delivery of quantum dots tagged antisense oligodeoxynucleotides by functionalized multiwalled carbon nanotubes. Nano Lett. doi: 10.1021/nl071114c (2007).
Top of pageDrug delivery: Wet or dry
Felix Cheung
Published online: 12 September 2007 | doi:10.1038/nchina.2007.188
Original article citation:
et al. Multiresponsive surfaces change between superhydrophilicity and superhydrophobicity. Adv. Mater. doi: 10.1002/adma.200602334 (2007).
Top of pageDNA analysis: Under the heat
Wei Zeng
Published online: 29 August 2007 | doi:10.1038/nchina.2007.174
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et al. DNA mutation detection with chip-based temperature gradient capillary electrophoresis using a slantwise radiative heating system. Lab Chip doi: 10.1039/b701649b (2007).
Top of pageAntibody mimetics: Smaller but better
Felix Cheung
Published online: 29 August 2007 | doi:10.1038/nchina.2007.176
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Small antibody mimetics comprising two complementarity-determining regions and a framework region for tumor targeting. Nature Biotechnol. 25, 921–929 (2007).
Top of pagePrenatal diagnostics: Finding the extra copy
Wei Zeng
Published online: 22 August 2007 | doi:10.1038/nchina.2007.170
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et al. Digital PCR for the molecular detection of fetal chromosomal aneuploidy. PNAS 104, 13116–13121 (2007).
Top of pageSensors: A snappy detector this content is Open !
Anne Pichon
Published online: 08 August 2007 | doi:10.1038/nchina.2007.154
Original article citation:
Reusable, label-free electrochemical aptasensor for sensitive detection of small molecules. Chem. Commun. doi: 10.1039/b707057h (2007).
Top of pageWater-quality management: A speedy sensor
Tim Reid
Published online: 08 August 2007 | doi:10.1038/nchina.2007.157
Original article citation:
An optical biosensing film for biochemical oxygen demand determination in seawater with an automatic flow sampling system. Meas. Sci. Technol. 18, 2878–2884 (2007).
Top of pageProtein structure: From loops to hoops this content is Open !
Hongfei Wang
Published online: 11 July 2007 | doi:10.1038/nchina.2007.133
Original article citation:
et al. IR spectroscopic discrimination between the loop and
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-helices and determination of the loop diffusion kinetics by T-jump time-resolved IR spectroscopy for cytochrome c. Biophys. J. doi: 10.1529/biophysj.107.106799 (2007). Fluorescent probes: A ball with two spikes
Wei Zeng
Published online: 04 July 2007 | doi:10.1038/nchina.2007.125
Original article citation:
et al. Hybrid silica-nanocrystal-organic dye superstructures as post-encoding fluorescent probes. Angew. Chem. Int. Edn doi: 10.1002/anie.200700847 (2007).
Top of pageArtificial vitreous: Plastic eye surgery this content is Open !
Wei Zeng
Published online: 20 June 2007 | doi:10.1038/nchina.2007.115
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et al. A new strategy to replace the natural vitreous by a novel capsular artificial vitreous body with pressure-control valve. Eye doi: 10.1038/sj.eye.6702875 (2007).
Top of pageNanochannels: Switchable membrane this content is Open !
Felix Cheung
Published online: 06 June 2007 | doi:10.1038/nchina.2007.96
Original article citation:
Tunable non-equilibrium gating of flexible DNA nanochannels in response to transport flux. Nature Nanotech. doi: 10.1038/nnano.2007.148 (2007).
Top of pageCarbon nanohorns: Miniature drug dealers
Tim Reid
Published online: 09 May 2007 | doi:10.1038/nchina.2007.76
Original article citation:
, , & Isolation of carbon nanohorn assemblies and their potential for intracellular delivery. Nanotechnol. 18, 195103 (2007).
Top of pageQuantum dots: Cell illuminators this content is Open !
Tim Reid
Published online: 09 May 2007 | doi:10.1038/nchina.2007.78
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, , & Gemini surfactant for fluorescent and stable quantum dots in solution. Nanotechnol. 18, 205603 (2007).
Top of pagePractical pharmacology: Getting under the skin this content is Open !
Kaspar Mossman
Published online: 31 January 2007 | doi:10.1038/nchina.2007.070131-1
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et al. Transdermal protein delivery by a coadministered peptide identified via phage display. Nature Biotech. 24, 455–460 (2006).
Top of pageEnvironmental detoxification: Green clean-up by root therapy
Kaspar Mossman
Published online: 18 January 2007 | doi:10.1038/nchina.2007.070118-19
Original article citation:
et al. Ex planta phytoremediation of trichlorophenol and phenolic allelochemicals via an engineered secretory laccase. Nature Biotechnol. 22, 893–897 (2004).
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