• Archive: Chemistry

    • Chemistry 2010 Research Highlights

      • Organic chemistry: A metal-free approach to biaryl synthesis Open !

        Felix Cheung

        Published online: 03 November 2010 | doi:10.1038/nchina.2010.119

        Original article citation:

        Sun, C. L. et al. An efficient organocatalytic method for constructing biaryls through aromatic C–H activation. Nature Chem. doi:10.1038/NCHEM.862 (2010).

      • Surface chemistry: Look beneath the water

        Anne Pichon

        Published online: 03 November 2010 | doi:10.1038/nchina.2010.120

        Original article citation:

        Luo, C. et al. Direct three-dimensional imaging of the buried interfaces between water and superhydrophobic surfaces. Angew. Chem. Int. Ed. doi:10.1002/anie.201002470 (2010).

      • Synthesis: The 17 steps to making grassypeptolide

        Anne Pichon

        Published online: 03 November 2010 | doi:10.1038/nchina.2010.121

        Original article citation:

        Liu, H., Liu, Y., Xing, X., Xu, Z. & Ye, T. Total synthesis of grassypeptolide. Chem. Commun. 46, 7486–7488(2010).

      • Drug discovery: Drug search

        Timon Chengyi Liu

        Published online: 06 October 2010 | doi:10.1038/nchina.2010.106

        Original article citation:

        Zhao, S. & Li, S. Network-based relating pharmacological and genomic spaces for drug target identification. PLoS ONE 5, e11764 (2010).

      • Chemical biology: A new twist in Alzheimer's disease Open !

        Anne Pichon

        Published online: 06 October 2010 | doi:10.1038/nchina.2010.107

        Original article citation:

        Geng, J., Zhao, C., Ren J. & Qu, X. Alzheimer's disease amyloid beta converting left-handed Z-DNA back to right-handed B-form. Chem. Commun. doi:10.1039/c0cc02049d (2010).

      • Catalysis: Iron awe

        Anne Pichon

        Published online: 06 October 2010 | doi:10.1038/nchina.2010.109

        Original article citation:

        Chow, T. W. S. et al. cis-dihydroxylation of alkenes with oxone catalyzed by iron complexes of a macrocyclic tetraaza ligand and reaction mechanism by ESI-MS spectrometry and DFT calculations. J. Am. Chem. Soc. doi:10.1021/ja100967g (2010).

      • General chemistry: Eight in a row Open !

        Felix Cheung

        Published online: 01 September 2010 | doi:10.1038/nchina.2010.100

        Original article citation:

        Li, Y. C. et al. 1,1′-azobis-1,2,3-triazole: a high-nitrogen compound with stable N8 structure and photochromism. J. Am. Chem. Soc. doi:10.1021/ja103525v (2010).

      • Electrochemistry: Long live the lithium battery Open !

        Felix Cheung

        Published online: 01 September 2010 | doi:10.1038/nchina.2010.99

        Original article citation:

        Luo, J. Y., Cui, W. J., He, P. & Xia, Y. Y. Raising the cycling stability of aqueous lithium-ion batteries by eliminating oxygen in the electrolyte. Nature Chem. doi:10.1038/nchem.763 (2010).

      • Synthesis: A little acid goes a long way

        Anne Pichon

        Published online: 04 August 2010 | doi:10.1038/nchina.2010.90

        Original article citation:

        Wang, Q., Zhang, M., Chen, C., Ma, W. & Zhao, J. Photocatalytic aerobic oxidation of alcohols on TiO2: the acceleration effect of a Brønsted acid. Angew. Chem. Int. Ed. doi:10.1002/anie.201001533 (2010).

      • Analytical chemistry: Sweet thoughts Open !

        Anne Pichon

        Published online: 07 July 2010 | doi:10.1038/nchina.2010.78

        Original article citation:

        Jiang, Y. et al. Colorimetric detection of glucose in rat brain using gold nanoparticles. Angew. Chem. Int. Ed. doi:10.1002/anie.201001057 (2010).

      • Electrochemistry: Making ends meet

        Anne Pichon

        Published online: 07 July 2010 | doi:10.1038/nchina.2010.79

        Original article citation:

        Yan, Q. et al. Voltage-responsive vesicles based on orthogonal assembly of two homopolymers. J. Am. Chem. Soc. doi:10.1021/ja1027502 (2010).

      • Catalysis: The right metal for a sustainable future Open !

        Felix Cheung

        Published online: 02 June 2010 | doi:10.1038/nchina.2010.66

        Original article citation:

        Zhu, S. F., Cai, Y., Mao, H. X., Xie, J. H. & Zhou, Q. L. Enantioselective iron-catalysed O-H bond insertions. Nature Chem. doi:10.1038/nchem.651 (2010).

      • Materials chemistry: Expanding the carbon family Open !

        Anne Pichon

        Published online: 02 June 2010 | doi:10.1038/nchina.2010.67

        Original article citation:

        Li, G. et al. Architecture of graphdiyne nanoscale films. Chem. Commun. 46, 3256–3258 (2010).

      • Materials chemistry: Unsuspected activity

        Anne Pichon

        Published online: 02 June 2010 | doi:10.1038/nchina.2010.72

        Original article citation:

        Lin, J. B., Zhang, J. P. & Chen, X. M. Nonclassical active site for enhanced gas sorption in porous coordination polymer. J. Am. Chem. Soc. doi:10.1021/ja1009635 (2010).

      • Medicinal chemistry: How arsenic stops leukaemia

        Felix Cheung

        Published online: 05 May 2010 | doi:10.1038/nchina.2010.62

        Original article citation:

        Zhang, X. W. et al. Arsenic trioxide controls the fate of the PML-RARα oncoprotein by directly binding PML. Science 328, 240–243 (2010).

      • Organic chemistry: No smoke without fire, and no fire without hydroperoxides Open !

        Felix Cheung

        Published online: 28 April 2010 | doi:10.1038/nchina.2010.59

        Original article citation:

        Battin-Leclerc, F. et al. Experimental confirmation of the low-temperature oxidation scheme of alkanes. Angew. Chem. Int. Ed. 49, 3169–3172 (2010).

      • Nanotechnology: Reopening the door to cancer treatment

        Anne Pichon

        Published online: 21 April 2010 | doi:10.1038/nchina.2010.53

        Original article citation:

        Liang, X. J. et al. Metallofullerene nanoparticles circumvent tumor resistance to cisplatin by reactivating endocytosis. Proc. Natl Acad. Sci. USA. doi:10.1073/pnas.0909707107 (2010).

      • Supramolecular chemistry: Cross cages Open !

        Felix Cheung

        Published online: 21 April 2010 | doi:10.1038/nchina.2010.54

        Original article citation:

        Kuang, X. et al. Assembly of a metal–organic framework by sextuple intercatenation of discrete adamantane-like cages. Nature Chem. doi:10.1038/nchem.618 (2010).

      • Nanotechnology: Negative proteins find their shelter

        Anne Pichon

        Published online: 14 April 2010 | doi:10.1038/nchina.2010.50

        Original article citation:

        Cao, A. et al. A facile method to encapsulate proteins in silica nanoparticles: encapsulated green fluorescent protein as a robust fluorescence probe. Angew. Chemie Int. Ed. doi:10.1002/anie.200906883 (2010).

      • Nanotechnology: Thin protection

        Anne Pichon

        Published online: 14 April 2010 | doi:10.1038/nchina.2010.51

        Original article citation:

        Lu, C. H. et al. Using graphene to protect DNA from cleavage during cellular delivery. Chem. Commun. doi:10.1039/b926893f (2010).

      • Physical chemistry: Resolved resonances Open !

        Felix Cheung

        Published online: 31 March 2010 | doi:10.1038/nchina.2010.42

        Original article citation:

        Dong, W. et al. Transition-state spectroscopy of partial wave resonances in the F + HD reaction. Science. 327, 1501–1502 (2010).

      • Sensors: A rainbow of colours

        Anne Pichon

        Published online: 31 March 2010 | doi:10.1038/nchina.2010.44

        Original article citation:

        Yan, Q. Dual-sensing porphyrin-containing copolymer nanosensor as full-spectrum colorimeter and ultra-sensitive thermometer. Chem. Comm. doi:10.1039/b926882k (2010).

      • Analytical chemistry: Smart dust Open !

        Felix Cheung

        Published online: 24 March 2010 | doi:10.1038/nchina.2010.37

        Original article citation:

        Li, J. F. et al. Shell-isolated nanoparticle-enhanced Raman spectroscopy. Nature 464, 392–395 (2010).

      • General chemistry: An inverted emulsion

        Anne Pichon

        Published online: 17 March 2010 | doi:10.1038/nchina.2010.35

        Original article citation:

        Sun, G., Li, Z. & Ngai, T. Inversion of particle-stabilized emulsions to form high-internal-phase emulsions. Angew. Chem. Int. Ed. doi:10.1002/anie.200907175 (2010).

      • Material chemistry: Romance of the three pentagons Open !

        Felix Cheung

        Published online: 03 March 2010 | doi:10.1038/nchina.2010.25

        Original article citation:

        Tan, Y. Z. et al. Chlorofullerenes featuring triple sequentially fused pentagons. Nature Chem. doi:10.1038/nchem.549 (2010).

      • Analytical chemistry: Nanoseparation goes organic

        Anne Pichon

        Published online: 24 February 2010 | doi:10.1038/nchina.2010.22

        Original article citation:

        Bai, L. et al. Rapid separation and purification of nanoparticles in organic density gradients. J. Am. Chem. Soc. doi:10.1021/ja908971d (2010).

      • Surface chemistry: Water on the web Open !

        Felix Cheung

        Published online: 24 February 2010 | doi:10.1038/nchina.2010.23

        Original article citation:

        Zheng, Y. et al. Directional water collection on wetted spider silk. Nature 463, 640–643 (2010).

      • Supramolecular chemistry: White emitters

        Anne Pichon

        Published online: 10 February 2010 | doi:10.1038/nchina.2010.17

        Original article citation:

        Lei, Y., Liao, Q., Fu, H. & Yao. J. Orange–blue–orange triblock one-dimensional heterostructures of organic microrods for white-light emission. J. Am. Chem. Soc. doi:10.1021/ja9084435 (2010).

      • Medicinal chemistry: Changing targets Open !

        Anne Pichon

        Published online: 03 February 2010 | doi:10.1038/nchina.2010.15

        Original article citation:

        Xue, Z. et al. Platinum(II) compounds bearing bone-targeting group: synthesis, crystal structure and antitumor activity. Chem. Commun. doi:10.1039/b922222g (2010).

      • Materials chemistry: DNA in the loop

        Anne Pichon

        Published online: 27 January 2010 | doi:10.1038/nchina.2010.10

        Original article citation:

        You, Y. Z., Yu, Z. Q., Cui, M. M. & Hong C. Y. Preparation of photoluminescent nanorings with controllable bioreducibility and stimuli-responsiveness. Angew. Chem. Int. Ed. doi:10.1002/anie.200906707 (2010).

      • Catalysis: Lower reactivity means more hydrogen

        Anne Pichon

        Published online: 20 January 2010 | doi:10.1038/nchina.2010.7

        Original article citation:

        Wen, C., Liu, Y., Guo, Y., Wang, Y. & Lu, G. Strategy to eliminate catalyst hot-spots in the partial oxidation of methane: enhancing its activity for direct hydrogen production by reducing the reactivity of lattice oxygen. Chem. Commun. doi:10.1039/b920725b (2010).

      • Nanotechnology: In search for a stable isomer

        Felix Cheung

        Published online: 13 January 2010 | doi:10.1038/nchina.2010.4

        Original article citation:

        Li, B. et al. Addition of carbene to the equator of C70 to produce the most stable C71H2 isomer: 2aH-2(12)a-homo(C70-D5h(6))[5,6]fullerene. Angew. Chem. Int. Ed. doi:10.1002/anie.200905263 (2009).

      • Materials chemistry: Pores breathe new life into polymers Open !

        Felix Cheung

        Published online: 06 January 2010 | doi:10.1038/nchina.2009.244

        Original article citation:

        Huang, J. et al. 3D-ordered macroporous poly(ionic liquid) films as multifunctional materials. Chem. Commun. doi:10.1039/b921280a (2009).

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