• Archive: Clinical medicine

    • Clinical medicine 2011 Research Highlights

      • Nutrition: The best kept secret to losing weight Open !

        Felix Cheung

        Published online: 02 November 2011 | doi:10.1038/nchina.2011.82

        Original article citation:

        Li, J. et al. Improvement in chewing activity reduces energy intake in one meal and modulates plasma gut hormone concentrations in obese and lean young Chinese men. Am. J. Clin. Nutr. 94, 709–716 (2011).

      • Cancer biology: Calcium protection

        Felix Cheung

        Published online: 05 October 2011 | doi:10.1038/nchina.2011.69

        Original article citation:

        Wang, J. L. et al. Calcium prevents tumorigenesis in a mouse model of colorectal cancer. PLoS ONE 6, e22566 (2011).

      • Medical biology: Vascular protection

        Edward Duca

        Published online: 03 August 2011 | doi:10.1038/nchina.2011.55

        Original article citation:

        Wong, W. T. et al. Adiponectin is required for PPARγ-mediated improvement of endothelial function in diabetic mice. Cell Metab. 14, 104–115 (2011).

      • Medical genetics: A man's worst enemy Open !

        Felix Cheung

        Published online: 03 August 2011 | doi:10.1038/nchina.2011.58

        Original article citation:

        Feng, H. et al. Cell cycle-related kinase is a direct androgen receptor-regulated gene that drives β-catenin/T cell factor-dependent hepatocarcinogenesis. J. Clin. Invest. doi:10.1172/JCI45967 (2011).

      • Public health: Better safe than sorry

        Felix Cheung

        Published online: 01 June 2011 | doi:10.1038/nchina.2011.41

        Original article citation:

        Zhang, F. et al. Effect of earlier initiation of antiretroviral treatment and increased treatment coverage on HIV-related mortality in China: a national observational cohort study. Lancet Infect. Dis. doi:10.1016/S1473-3099(11)70097-4 (2011).

      • Public health: Rural virus turns a ruckus

        Edward Duca

        Published online: 04 May 2011 | doi:10.1038/nchina.2011.32

        Original article citation:

        Yu, X. J. et al. Fever with thrombocytopenia associated with a novel bunyavirus in China. N. Engl. J. Med. 364, 1523–1532 (2011).

      • Medical genetics: Follow your heart

        Felix Cheung

        Published online: 04 May 2011 | doi:10.1038/nchina.2011.35

        Original article citation:

        Wang, F. et al. Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nature Genet. 43, 345–351 (2011).

      • Gene therapy: Little RNA keeps cancer away

        Felix Cheung

        Published online: 06 April 2011 | doi:10.1038/nchina.2011.19

        Original article citation:

        Jin, H. et al. Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell 19, 232–243 (2011).

      • Preventive medicine: Breathing easy

        Edward Duca

        Published online: 06 April 2011 | doi:10.1038/nchina.2011.22

        Original article citation:

        Zhou, Y. et al. Community based integrated intervention for prevention and management of chronic obstructive pulmonary disease (COPD) in Guangdong, China: cluster randomised controlled trial. Br. Med. J. 341, c6387 (2010).

      • Medical biology: To my heart's keeper Open !

        Felix Cheung

        Published online: 02 March 2011 | doi:10.1038/nchina.2011.11

        Original article citation:

        Wang, J. X. et al. miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1. Nature Med. 17, 71–79 (2011).

      • Oncology: Soy joy Open !

        Felix Cheung

        Published online: 02 February 2011 | doi:10.1038/nchina.2010.138

        Original article citation:

        Kang, X., Zhang, Q., Wang, S., Huang, X. & Jin, S. Effect of soy isoflavones on breast cancer recurrence and death for patients receiving adjuvant endocrine therapy. Can. Med. Assoc. J. 182, 1857–1862 (2010).

      • Public health: Safe and effective

        Felix Cheung

        Published online: 02 February 2011 | doi:10.1038/nchina.2010.140

        Original article citation:

        Wu, J. et al. Safety and effectiveness of a 2009 H1N1 vaccine in Beijing. N. Engl. J. Med. 363, 2416–2423 (2010).

      • Pharmacology: Brain protection Open !

        Felix Cheung

        Published online: 05 January 2011 | doi:10.1038/nchina.2011.139

        Original article citation:

        Zhou, L. et al. Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95. Nature Med. 16, 1439–1444 (2010).

      • Neuroimaging: Mind the details Open !

        Felix Cheung

        Published online: 05 January 2011 | doi:10.1038/nchina.2011.144

        Original article citation:

        Li, A. et al. Micro-optical sectioning tomography to obtain a high-resolution atlas of the mouse brain. Science 300, 1404–1408 (2010).

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