Principal Scientist - Oncology Translational Research

With a commitment on turning good ideas into innovative, effective medicines for many unmet health needs, AstraZeneca is establishing a global research center in Zhangjiang Hi-tech Park, Shanghai, China: the Innovation Center China (ICC). The initial research area for ICC will be cancer research, with focus on translational science by developing knowledge about Chinese patients, discovering biomarkers for personalized medical needs and better understanding drug mechanisms of action for targeted therapies.

As a newly established global research center, ICC provides many excellent scientific research opportunities in a highly stimulating, diverse scientific environment, an active interaction with key opinion leaders in the related scientific fields, and a competitive career development path. ICC offers competitive salaries, compensation and benefits programs.

You are welcomed to send your CV to Joy.Wang@AstraZeneca.com

Address: Building 7, No. 898 Halei Road, Zhangjiang Hi-Tech Park, Shanghai 201203 China
Tel: 8621-61097812
Fax: 8621-61097700

Position Description:

As a translational scientist at ICC, you will initiate and execute translational science research and provide scientific strategies in support of the global drug discovery and development programs. The successful candidate will lead a group of cross-function scientists in cell biology, in vivo pharmacology, genetics and immunohistochemistry, and deliver translational data packages to guide and support clinical development of our candidate drugs. In addition, you will initiate and manage external scientific interaction and collaborations with the key opinion leaders in the related fields.

Requirements:

• MD or PhD in Biological or Medical Sciences with significant research experience in one of the following biological effect areas: growth factor/survival and angiogenesis
• 5+ years research experience in at least one of the three biological effect areas
• Experience in biomarker identification, shRNA or RNAi target validation & potential therapeutic application, and/or in vitro and/or in vivo models for solid tumors and applying these models for small molecules and biologicals studies essential
• Pharmaceutical (discovery) experience in small molecule or/and biologics drug discovery desired. Good understanding on key issues of translational science and how to apply translational science for drug discovery and development
• Demonstrated independent and collaborative and team-leading capabilities
• Strong commitment to team work as well as high levels of integrity, professionalism and personal ethics
• Excellent interpersonal, oral, and written presentation skills, and fluent in English and Chinese desired

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