Principal Scientist / Team Leader, In vitro biology

With a commitment on turning good ideas into innovative, effective medicines for many unmet health needs, AstraZeneca is establishing a global research center in Zhangjiang Hi-tech Park, Shanghai, China: the Innovation Center China (ICC). The initial research area for ICC will be cancer research, with focus on translational science by developing knowledge about Chinese patients, discovering biomarkers for personalized medical needs and better understanding drug mechanisms of action for targeted therapies.

As a newly established global research center, ICC provides many excellent scientific research opportunities in a highly stimulating, diverse scientific environment, an active interaction with key opinion leaders in the related scientific fields, and a competitive career development path. ICC offers competitive salaries, compensation and benefits programs.

You are welcomed to send your CV to Joy.Wang@AstraZeneca.com

Address: Building 7, No. 898 Halei Road, Zhangjiang Hi-Tech Park, Shanghai 201203 China
Tel: 8621-61097812
Fax: 8621-61097700

Position Description:

As a Principal Scientist I/Team Leader in ICC, you will manage and execute discovery and pre-clinical research projects and provide scientific strategies in support of the global drug discovery and development programs. The successful candidate will lead a group of in vitro pharmacology scientists with expertise in the biological effect areas including cell growth/survival signaling, angiogenesis, invasion and DNA repair/cell cycle. Also, this position will coordinate with the translational scientists to deliver translational data packages to guide and support clinical development of our candidate drugs.

Requirements:

You hold a MD or PhD in Biological or Medical Sciences and have 5+ years research experience in cancer cell biology and signaling. Experience in mechanism-based, target-driven in vitro culture and assay systems of cancer cells and applying these systems for small molecules and biologics evaluation is essential. Pharmaceutical (discovery) experience is also preferred. Demonstrated independent, collaborative and team-leading capability is another prerequisite to meet this challenge.

You have worked in an international environment and demonstrated excellent leadership and cross-functional communication ability.

You are committed to team leading with a high level of professionalism, personal ethics and a can-do attitude. You are motivated by challenges and you have a profound passion for science and research.

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