Disease Team Leader

With a commitment on turning good ideas into innovative, effective medicines for many unmet health needs, AstraZeneca is establishing a global research center in Zhangjiang Hi-tech Park, Shanghai, China: the Innovation Center China (ICC). The initial research area for ICC will be cancer research, with focus on translational science by developing knowledge about Chinese patients, discovering biomarkers for personalized medical needs and better understanding drug mechanisms of action for targeted therapies.

As a newly established global research center, ICC provides many excellent scientific research opportunities in a highly stimulating, diverse scientific environment, an active interaction with key opinion leaders in the related scientific fields, and a competitive career development path. ICC offers competitive salaries, compensation and benefits programs.

You are welcomed to send your CV to Joy.Wang@AstraZeneca.com

Address: Building 7, No. 898 Halei Road, Zhangjiang Hi-Tech Park, Shanghai 201203 China
Tel: 8621-61097812
Fax: 8621-61097700

Position Description:

We are seeking a highly motivated Ph.D/MD level scientist with broad knowledge and research experience in disease of hepatocellular carcinoma or/and gastric cancer to lead a group at the new AstraZeneca R&&D site in Shanghai, the Innovation Center China (ICC). The successful candidate will be able to independently guide, design and execute experiments to enhance the disease knowledge, and to identify and validate new targets using both pre-clinical models and clinical samples, and also to provide strategy for drug discovery and early clinical development.

Key Responsibilities:

• Plan, implement and organize molecular characterization of hepatocellular carcinoma and gastric cancer to provide baseline information
• Lead target selection, validation and potential biomarker identification
• Understand organ dysfunction and the impact on therapies
• Identify and establish models relevant to the diseases
• Monitor new therapies and emerging drug candidates
• Develop disease expertise, understand major unmet needs, and major disease segment
• Provide scientific leadership in future direction and strategy in the relevant disease from drug discovery and development perspective
• Familiar with current knowledge of agents and standard of cares used in the diseases
• Familiar with drug discovery and development
• Perform as an effective leader who supervises and coaches research scientists
• Effectively and collaboratively work with other functional and project teams
• Initiate and manage scientific collaborations in support of disease strategy
• Engage with the KOLs in the relevant fields

Minimum Requirements:

• Ph.D and MD or Ph.D with Medial background/training in biological science with a minimum of 5-8 years experience with proven track record in hepatocellular cancer or gastric cancer
• Excellent communication skills and ability to lead a team in a project team-oriented environment are essential
• A strong scientific curiosity and a "can-do" attitude are required to be successful for this position

Preferred Background:

• HBV research experience
• In vivo Cancer biology, Pharmacology
• Extensive cell biology and signal transduction research experience
• Pharmaceutical industry experience

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